Ibrance 125mg 25’s Tablets (Palbocicib)

Uses of the Ibrance 125mg Tablets

Ibrance 125mg (palbociclib) is a medication used to treat a specific type of advanced breast cancer in adults. It’s specifically designed to treat:

HR-positive (hormone receptor-positive) breast cancer: This means the cancer’s growth is stimulated by hormones like estrogen or progesterone.

HER2-negative breast cancer: This means the cancer cells don’t have abnormally high levels of a protein called HER2.

How Does Ibrance 125mg Tablet Work?

Ibrance (palbociclib) is a targeted therapy, meaning it specifically targets cancer cells without harming healthy cells. It works by:

Blocking CDK4 and CDK6 enzymes: These enzymes are proteins involved in cell growth and division. By blocking them, Ibrance slows down the growth and spread of cancer cells.

Essentially, Ibrance acts as a brake on cancer cell growth, giving the body a better chance to fight the disease.

How Should You?

Ibrance 125mg tablets are typically taken in a specific cycle:

3 weeks on: You take one tablet daily for 21 days.
1 week off: You do not take Ibrance for 7 days.

Swallow the tablet whole: Do not chew, crush, or split it.
Timing: While you can take it with or without food, it’s best to take it at the same time each day for consistency.
Avoid grapefruit: Grapefruit can interact with Ibrance, so it’s best to avoid it.

Ibrance 125mg 25s Tablets contain the active ingredient Palbociclib, a targeted therapy used in the treatment of certain types of advanced or metastatic breast cancer. It belongs to a class of medications called CDK4/6 inhibitors, which work by blocking proteins that promote cancer cell growth. Ibrance is typically used in combination with hormone therapy, such as letrozole or fulvestrant, for postmenopausal women or men with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) breast cancer.

Key Uses:

• Treatment of HR+/HER2− advanced or metastatic breast cancer
• Used in combination with hormone therapy
• Helps slow cancer progression
• Improves progression-free survival

How It Works:

Ibrance targets and inhibits cyclin-dependent kinases 4 and 6 (CDK4/6). These enzymes are involved in cell division. By blocking them, Ibrance helps to stop cancer cells from multiplying, thereby slowing tumor growth and helping control the disease.

Dosage & Administration:

• Typical dose: One 125mg tablet taken once daily for 21 consecutive days, followed by a 7-day break (28-day cycle)
• Take with food, preferably at the same time each day
• Dose adjustments may be required based on side effects or lab results
• Must be prescribed and monitored by an oncologist

Side Effects:

Common side effects include:

• Low white blood cell count (neutropenia)
• Fatigue
• Nausea
• Hair thinning or loss
• Mouth sores
• Diarrhea

Serious side effects may include infections due to low immunity, liver function changes, or blood clots. Regular blood tests are needed during treatment.

Precautions:

• Not suitable during pregnancy or breastfeeding
• Effective birth control is recommended during and for at least 3 weeks after the last dose
• Avoid grapefruit juice, which may increase drug levels in the blood
• Inform your doctor about all other medications you are taking

Availability in Pakistan:

Ibrance 125mg 25s Tablets are available in leading pharmacies and online medical platforms in Pakistan. It is a prescription-only oncology medication, and treatment should be initiated and supervised by a qualified cancer specialist.