Norditropin NordiFlex 5 mg / 1.5 ml injection

Norditropin NordiFlex 5mg/1.5ml Injection is a recombinant human growth hormone (Somatropin) used to treat growth hormone deficiency (GHD) in children and adults. It stimulates growth, increases height in children with GHD, and helps improve body composition in adults by promoting lean muscle mass and reducing body fat.

The NordiFlex device is a pre-filled, ready-to-use injection pen that ensures accurate dosing and easy self-administration. Each pen contains 5mg of Somatropin in 1.5ml solution. The injection is administered subcutaneously and is typically used once daily, as per the physician’s instructions.

Norditropin is indicated for:

Pediatric patients with growth failure due to GHD, Turner syndrome, Noonan syndrome, or chronic renal insufficiency.

Adults with adult-onset or childhood-onset GHD.

Children born small for gestational age (SGA) who fail to catch up in growth.

Administration should follow a tailored dosage regimen determined by your doctor based on weight, age, and therapeutic goals. Proper rotation of injection sites (thigh, abdomen) helps prevent lipodystrophy.

Possible side effects include injection site reactions, joint pain, muscle pain, edema, and headaches. Serious adverse effects like intracranial hypertension or glucose metabolism disorders are rare but require immediate medical attention.

Store the NordiFlex pen in a refrigerator at 2°C to 8°C. Once in use, it can be stored at room temperature (up to 25°C) for up to 21 days.

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Description

Norditropin NordiFlex 5mg/1.5ml Injection (Somatropin)

Norditropin NordiFlex 5mg/1.5ml Injection is a recombinant human growth hormone used to treat growth hormone deficiency (GHD) in both children and adults. In children, it promotes linear growth, while in adults, it improves body composition and overall metabolic health.

The NordiFlex system features a pre-filled, user-friendly injection pen designed for easy home administration. Each pen contains 5mg of Somatropin in 1.5ml of solution, allowing for accurate dosing with minimal waste and maximum convenience.

Indications

  • Growth failure in children caused by GHD, Turner syndrome, Noonan syndrome, or chronic renal insufficiency
  • Children born small for gestational age (SGA) who have not achieved expected growth milestones
  • Adults with either childhood-onset or adult-onset GHD, confirmed through diagnostic testing

Dosage and Administration

The dosage is tailored individually based on age, weight, and treatment response. Typically, children receive daily subcutaneous injections in the evening, while adults start with lower doses that are gradually adjusted to maintain healthy IGF-1 levels.

For safe administration, rotate injection sites—such as the abdomen, thigh, or upper arm—to prevent lipodystrophy (localized fat changes). Patients or caregivers must be trained in proper pen usage to ensure effective delivery.

Possible Side Effects

Common side effects include mild injection site irritation, joint stiffness, muscle pain, headaches, and fluid retention. Although rare, serious effects such as increased intracranial pressure, slipped capital femoral epiphysis, or glucose intolerance require prompt medical attention.

Storage Instructions

Store unopened pens in a refrigerator (2°C to 8°C). After first use, you may keep the pen at room temperature (up to 25°C) for a maximum of 21 days. Do not freeze or expose the pen to direct sunlight. Always keep it out of children’s reach.

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